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FITC標記的轉錄因子相關蛋白NK2抗體

文字:[大][中][小] 2017-5-3    瀏覽次數:1507    

                                   FITC標記的轉錄因子相關蛋白NK2抗體                                                                                                                                                
英文名稱Anti-NKX1-2/FITC
中文名稱FITC標記的轉錄因子相關蛋白NK2抗體
別    名BB238F13.2; C10orf121; Homeobox protein SAX-1; NK1 homeobox 2; NK1 transcription factor related locus 2; NK1 transcription factor-related protein 2; NKX-1.1; NKX1-2; NKX12_MOUSE; Sax1; Sax1-like; Spinal cord axial homeobox gene 1.  

詳細介紹:


規格:100ug     
說 明 書100ug  
研究領域細胞生物  神經生物學  轉錄調節因子  表觀遺傳學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應 Mouse, 
產品應用ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量32kDa
性    狀Lyophilized or Liquid
濃    度2mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from mouse NKX1-2
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

相關資料:


產品介紹background:
NKX1-2 (NK1 Homeobox 2) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is NKX1-1.

Function:
May function in cell specification, particularly in the CNS.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expression detected in adult brain, testis and spleen. In the testis, expressed in the germ cells of the seminiferous epithelium, in elongating spermatids and in spermatozoa. Expressed throughout the brain with highest levels in regions of the cerebral cortex, hippocampus, diencephalon, pons, medulla and cerebellum. In the embryo, expressed in the developing posterior central nervous system. First seen in the ectoderm lateral to the primitive streak, later it encompasses the neural plate. Starting at day 9.5 pc, expressed in distinct areas of spinal cord, hindbrain, midbrain and forebrain.

Post-translational modifications:
Phosphorylated by HIPK2 in vitro.

Similarity:
Belongs to the NK-1 homeobox family.
Contains 1 homeobox DNA-binding domain.
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